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Zoltan Kiss Fat Research, a privately owned biotechnological company, has two research goals, namely (1) provide a reliable animal model with no confounding factors to help clarify the roles of excess visceral fat in physiological disorders with the help of a model composed of obese mice and two nontoxic human proteins (ZKPr1 and ZKPr2), and (2) provide sufficiently convincing research data for the obesity research community and drug companies that may lead them to consider development of one of these proteins (ZKPr1) for the normalization of excess visceral fat and inducing substantial weight loss along with the improvement of practically all associated metabolic disorders.
Three examples of visceral vs subcutaneous fat localization are shown. The first patient (a) demonstrates high visceral fat content (blue) relative to subcutaneous fat (orange), compatible with an "apple-shaped" body habitus (belly fat). The second patient (b) demonstrates the "pear-shaped" body habitus, with relative increase in subcutaneous fat over visceral fat. The third patient (c) demonstrates a more balanced state of obesity, with large amounts of both visceral and subcutaneous fat. [Credit: Peter Graffy and Perry J. Pickhardt: Quantification of Hepatic and Visceral Fat by CT and MR Imaging: Relevance to the Obesity Epidemic, Metabolic Syndrome, and NAFLD; British Journal of Radiology. 2016;89:20151024.]Three examples of visceral vs subcutaneous fat localization are shown. The first patient (a) demonstrates high visceral fat content (blue) relative to subcutaneous fat (orange), compatible with an "apple-shaped" body habitus (belly fat). The second patient (b) demonstrates the "pear-shaped" body habitus, with relative increase in subcutaneous fat over visceral fat. The third patient (c) demonstrates a more balanced state of obesity, with large amounts of both visceral and subcutaneous fat. [Credit: Peter Graffy and Perry J. Pickhardt: Quantification of Hepatic and Visceral Fat by CT and MR Imaging: Relevance to the Obesity Epidemic, Metabolic Syndrome, and NAFLD; British Journal of Radiology. 2016;89:20151024.]